PLD6 rabbit pAb

CAT: 0855-ES14067-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:0855-ES14067-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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UniProt

Q8N2A8

Swiss Prot

Q8N2A8

Reactivity

Human; Mouse

Immunogen

Synthesized peptide derived from human PLD6 AA range: 29-79

Target

PLD6

Clonality

Polyclonal

Source

Rabbit

Applications

WB; IHC

Concentration

1 mg/ml

Dilution

WB 1:500-2000; IHC-p 1:50-300

Buffer

-20°C/1 year

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

Mitochondrion outer membrane ; Single-pass membrane protein . Golgi apparatus . Localization in the mitochondrial outer membrane is found in different cell types where phospholipase is the predominant activity, however, in pachytene spermatocytes and spermatids of mouse testes where nuclease activity is predominant, localization is restricted to the Golgi, suggesting this enzyme is localized in different subcellular compartments depending on the role (phospholipase or nuclease) it needs to play in each cell type and developmental stage. .

Gene ID (Human)

201164

UniProtKB · Q8N2A8

Mitochondrial cardiolipin hydrolase

PLD6_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q8N2A8
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: PLD6
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: 3.1.4.-
Processing: —
Secondary accessions: Q8N5Y1

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Biological process

DifferentiationLipid degradationLipid metabolismMeiosisSpermatogenesis

Molecular function

EndonucleaseHydrolaseNuclease

Cellular component

Golgi apparatusMembraneMitochondrionMitochondrion outer membrane

Ligand

Metal-bindingZinc

Domain

TransmembraneTransmembrane helixZinc-finger

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