BDZ-g

• Description:

  BDZ-g is a potent, selective antagonist of AMPA receptor. BDZ-g has the potential for the research of various neurological disorders involving excessive activity of AMPA receptors[1].

• UNSPSC:

  12352005

• Target:

  IGluR

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/bdz-g.html

• Purity:

  98.0

• Solubility:

  10 mM in DMSO

• Smiles:

  CC(C=C(C=C1)C(C2=C(C3)C=C4C(OCO4)=C2)=NN(C(S5)=NN=C5C)[C@@H]3C)=C1N

• Molecular Formula:

  C21H21N5O2S

• Molecular Weight:

  407.49

• References & Citations:

  [1]Wang C, et al. Mechanism and site of inhibition of AMPA receptors: pairing a thiadiazole with a 2,3-benzodiazepine scaffold. ACS Chem Neurosci. 2014;5 (2) :138-147.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, protect from light, stored under nitrogen)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  AMPA Receptor

• CAS Number:

  [732278-52-3]