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BDZ-g

CAT: 0804-HY-129030-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-129030-01Size:1 mg
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Description
BDZ-g is a potent, selective antagonist of AMPA receptor. BDZ-g has the potential for the research of various neurological disorders involving excessive activity of AMPA receptors[1].
CAS Number
732278-52-3
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bdz-g.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
CC(C=C(C=C1)C(C2=C(C3)C=C4C(OCO4)=C2)=NN(C(S5)=NN=C5C)[C@@H]3C)=C1N
Molecular Formula
C21H21N5O2S
Molecular Weight
407.49
References & Citations
[1]Wang C, et al. Mechanism and site of inhibition of AMPA receptors: pairing a thiadiazole with a 2,3-benzodiazepine scaffold. ACS Chem Neurosci. 2014;5 (2) :138-147.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AMPA Receptor