Mupirocin (Standard)

• Description:

  Mupirocin (Standard) is the analytical standard of Mupirocin (HY-B0958) . This product is intended for research and analytical applications. Mupirocin is an antibiotic. Mupirocin inhibits bacterial isoleucyl-tRNA synthetase, blocking protein synthesis. Mupirocin has high activity against Gram-positive bacteria such as Staphylococcus and Streptococcus, as well as some Gram-negative bacteria (such as Haemophilus influenzae) . Mupirocin can be used in the research of diseases such as skin infections (such as MRSA infections) and chronic sinusitis[1][2][3][4][5][6].

• Product Name Alternative:

  BRL-4910A (Standard) ; Pseudomonic acid (Standard)

• UNSPSC:

  12352005

• Target:

  Aminoacyl-tRNA Synthetase; Antibiotic; Bacterial; Reference Standards

• Type:

  Reference Standards

• Related Pathways:

  Anti-infection; Metabolic Enzyme/Protease; Others

• Field of Research:

  Infection; Endocrinology

• Assay Protocol:

  https://www.medchemexpress.com/mupirocin-standard.html

• Smiles:

  O[C@@H]1[C@@](CO[C@@H](C/C(C)=C/C(OCCCCCCCCC(O)=O)=O)[C@@H]1O)([H])C[C@H]2[C@@]([C@@H](C)[C@@H](O)C)([H])O2

• Molecular Formula:

  C26H44O9

• Molecular Weight:

  500.62

• References & Citations:

  [1]Sutherland R, et al. Antibacterial activity of mupirocin (pseudomonic acid), a new antibiotic for topical use. Antimicrob Agents Chemother. 1985 Apr;27 (4) :495-8.|[2]Parenti MA, et al. Mupirocin: a topical antibiotic with a unique structure and mechanism of action. Clin Pharm. 1987 Oct;6 (10) :761-70.|[3]Vingsbo Lundberg C, et al. Efficacy of topical and systemic antibiotic treatment of meticillin-resistant Staphylococcus aureus in a murine superficial skin wound infection model. Int J Antimicrob Agents. 2013 Sep. 42 (3) :272-5.|[4]Mohammad H, Abutaleb NS, Dieterly AM, Lyle LT, Seleem MN. Investigating auranofin for the treatment of infected diabetic pressure ulcers in mice and dermal toxicity in pigs. Sci Rep. 2021 May 25;11 (1) :10935.|[5]Giacometti A, et al. Mupirocin prophylaxis against methicillin-susceptible, methicillin-resistant, or vancomycin-intermediate Staphylococcus epidermidis vascular-graft infection. Antimicrob Agents Chemother. 2000 Oct. 44 (10) :2842-4.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  [12650-69-0]