KIF18A-IN-13

KIF18A-IN-13

• CAS Number: 3029503-57-6
• UNSPSC Description: KIF18A-IN-13 (Compound 16) is an effective and orally active inhibitor of KIF18A with anticancer activity in vivo. KIF18A-IN-13 can be utilized for research in ovarian cancer[1].
• Target Antigen: Kinesin; Microtubule/Tubulin
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Cytoskeleton
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/kif18a-in-13.html
• Smiles: O=C(C1=CC=C(NS(=O)(CCO)=O)C=C1C2=CCC3(CC3)CC2)NC4=CC(C)=CC(N5CCC(F)(F)CC5)=N4
• Molecular Weight: 560.66
• References & Citations: [1]Zhang C, et al. Design, Biological Characterization, and Discovery of Novel Cyclohexenyl Derivatives as Kinesin KIF18A Inhibitors for the Treatment of Ovarian Cancer[J]. ACS Medicinal Chemistry Letters, 2024.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported