Maprotiline (hydrochloride) (Standard)

Maprotiline (hydrochloride) (Standard)

• CAS Number: 10347-81-6
• UNSPSC Description: Maprotiline (hydrochloride) (Standard) is the analytical standard of Maprotiline (hydrochloride). Maprotiline (hydrochloride) (Standard) is a highly selective noradrenergic reuptake inhibitor that has strong antidepressant, antitumor and neuropathic pain-relieving effects. Maprotiline (hydrochloride) (Standard) induces cancer cell apoptosis by targeting the ERK signaling pathway and CRABP1[1][2].
• Target Antigen: Apoptosis; Autophagy; ERK
• Type: Reference Standards
• Related Pathways: Apoptosis;Autophagy;MAPK/ERK Pathway;Stem Cell/Wnt
• Field of Research: Neurological Disease; Cancer
• Assay Protocol: https://www.medchemexpress.com/maprotiline-hydrochloride-standard.html
• Purity: 99.99
• Smiles: CNCCCC1(CC2)C3=CC=CC=C3C2C4=CC=CC=C14.Cl
• Molecular Weight: 313.86
• References & Citations: [1]Zheng C, et al. Maprotiline Suppresses Cholesterol Biosynthesis and Hepatocellular Carcinoma Progression Through Direct Targeting of CRABP1. Front Pharmacol. 2021 May 20. 12:689767.|[2]Gunduz O, et al. Analysis of the anti-allodynic effects of combination of a synthetic cannabinoid and a selective noradrenaline re-uptake inhibitor in nerve injury-induced neuropathic mice. Eur J Pain. 2016 Mar. 20(3):465-71.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture and light)
• Clinical Information: Launched