Methyl pyropheophorbide-a

Methyl pyropheophorbide-a

• CAS Number: 6453-67-4
• UNSPSC Description: Methyl pyropheophorbide-a (Pyropheophorbide-a methyl ester), a chlorophyll-a derivative, is a potent photosensitizer that can be used in photodynamic therapy (PDT) of cancer. Methyl pyropheophorbide-a has photodynamic activity and can induce apoptosis and inhibit tumor growth[1][2].
• Target Antigen: Apoptosis
• Type: Reference compound
• Related Pathways: Apoptosis
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/methyl-pyropheophorbide-a.html
• Smiles: CC1=C(N2)/C=C(C(CC)=C3C)\N=C3/C=C(C(C=C)=C/4C)\NC4=C/C5=N/C([C@H]([C@@H]5C)CCC(OC)=O)=C(C6)\C2=C1C6=O
• Molecular Weight: 548.67
• References & Citations: [1]Sun X, et, al. Photodynamic therapy with pyropheophorbide-a methyl ester in human lung carcinoma cancer cell: efficacy, localization and apoptosis. Photochem Photobiol. 2002 Jun;75(6):644-51.|[2]Tian Y, et, al. Cell death induced by MPPa-PDT in prostate carcinoma in vitro and in vivo. Biochem Biophys Res Commun. 2006 Sep 22;348(2):413-20.
• Shipping Conditions: Room Temperature