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Methyl pyropheophorbide-a

CAT: 0804-HY-137473-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-137473-01Size:5 mg
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Description
Methyl pyropheophorbide-a (Pyropheophorbide-a methyl ester), a chlorophyll-a derivative, is a potent photosensitizer that can be used in photodynamic therapy (PDT) of cancer. Methyl pyropheophorbide-a has photodynamic activity and can induce apoptosis and inhibit tumor growth[1][2].
CAS Number
6453-67-4
Product Name Alternative
Pyropheophorbide-a methyl ester
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/methyl-pyropheophorbide-a.html
Purity
99.14
Solubility
DMSO : 2.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CC1=C(N2)/C=C(C(CC)=C3C)\N=C3/C=C(C(C=C)=C/4C)\NC4=C/C5=N/C([C@H]([C@@H]5C)CCC(OC)=O)=C(C6)\C2=C1C6=O
Molecular Formula
C34H36N4O3
Molecular Weight
548.67
References & Citations
[1]Sun X, et, al. Photodynamic therapy with pyropheophorbide-a methyl ester in human lung carcinoma cancer cell: efficacy, localization and apoptosis. Photochem Photobiol. 2002 Jun;75 (6) :644-51.|[2]Tian Y, et, al. Cell death induced by MPPa-PDT in prostate carcinoma in vitro and in vivo. Biochem Biophys Res Commun. 2006 Sep 22;348 (2) :413-20.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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