Products for Research Use Only
RegisterLogin

Meldonium

CAT: 0804-HY-B1836-01Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-B1836-01Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Meldonium (MET-88) functions as a cardioprotective agent by cpmpetetively inhibiting γ-butyrobetaine hydroxylase (BBOX) and carnitine/organic cation transporter type 2 (OCTN2) . Meldonium exhibits IC50 values of 34-62 μM for human recombinant BBOX and an EC50 of 21 μM for human OCTN2. Meldonium is a fatty acid oxidation inhibitor[1][2].
CAS Number
76144-81-5
Product Name Alternative
MET-88; Quaterin
UNSPSC
12352211
Hazard Statement
H315, H319, H335
Target
Mitochondrial Metabolism
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/meldonium.html
Purity
99.89
Solubility
H2O : 50 mg/mL (ultrasonic)
Smiles
C[N+](C)(C)NCCC([O-])=O
Molecular Formula
C6H14N2O2
Molecular Weight
146.19
Precautions
H315, H319, H335
References & Citations
[1]Dambrova M, et al. Pharmacological effects of meldonium: Biochemical mechanisms and biomarkers of cardiometabolic activity. Pharmacol Res. 2016 Nov;113 (Pt B) :771-780.|[2]Jolanta Pupure, et al. Neuroprotective properties of mildronate, a mitochondria-targeted small molecule. Neurosci Lett. 2010 Feb 12;470 (2) :100-5.|[3]Daohui Wang, et al. Meldonium Ameliorates Hypoxia-Induced Lung Injury and Oxidative Stress by Regulating Platelet-Type Phosphofructokinase-Mediated Glycolysis. Front Pharmacol. 2022 Apr 5:13:863451.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Citation 01
J Anim Sci. 2022 Apr 1;100 (4) :skac069.|Nat Commun. 2025 Feb 11;16 (1) :1543.|J Pharm Biomed Anal. 2021 Feb 20:195:113870.

Alternative Products

CatalogName
sc-207887Meldonium
sc-483554Meldonium dihydrate
A12316-100Meldonium 100mg
A12316-50Meldonium 50mg
RM-M551001-01Meldonium EP Impurity D
RM-M551002-01Meldonium EP Impurity E
BT164669Meldonium dihydrate - Bio-X TM

Popular Products