(S) -Azelastine

• Description:

  (S) -Azelastine ((+) -Azelastine) is an antihistamine with antiallergic and antiasthmatic activity. (S) -Azelastine has been shown to downregulate H1R, M1R, and M3R levels. (S) -Azelastine also has the property of inhibiting HNEpC proliferation[1].

• Product Name Alternative:

  (+) -Azelastine

• UNSPSC:

  12352005

• Target:

  Histamine Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/s-azelastine.html

• Smiles:

  O=C1C2=CC=CC=C2C (CC3=CC=C (C=C3) Cl) =NN1[C@H]4CCCN (CC4) C

• Molecular Formula:

  C22H24ClN3O

• Molecular Weight:

  381.90

• References & Citations:

  [1]Chirality of Azelastine and Flezelastine: Investigation of Their Enantiomers

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  143228-85-7