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Lithium salicylate

CAT: 0804-HY-B1681Size: 1 EachDry Ice: NoHazardous: No
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Description
Lithium salicylate (Salicylic acid lithium) is an orally active lithium salt. Lithium salicylate (Salicylic acid lithium) attenuates tau phosphorylation, mitigates associated pathologies in Alzheimer’s mice. Lithium salicylate (Salicylic acid lithium) can be used for Alzheimer’s research[1].
CAS Number
552-38-5
Product Name Alternative
Salicylic acid (lithium) ; 2-Hydroxybenzoic acid (lithium)
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
Tau Protein
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C(C1=C(O)C=CC=C1)O[Li]
Molecular Formula
C7H5LiO3
Molecular Weight
144.05
Precautions
P264-P270-P280-P302+P352-P330-P362+P364-P501
References & Citations
[1]Habib A, et al. LISPRO mitigates β-amyloid and associated pathologies in Alzheimer's mice. Cell Death Dis. 2017 Jun 15;8 (6) :e2880. doi: 10.1038/cddis.2017.279. Retraction in: Cell Death Dis. 2021 Dec 9;12 (12) :1142.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

Lithium Salicylate

See also: Dilithium salicylate (annotation moved to).

CAS Number552-38-5
PubChem CID23663621
IUPAC Namelithium 2-hydroxybenzoate
Molecular FormulaC7H5LiO3
Molecular Weight144.1
Topological Polar Surface Area60.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Heavy Atom Count11
Formal Charge0
Complexity138
SMILES
[Li+].C1=CC=C(C(=C1)C(=O)[O-])O
InChI
InChI=1S/C7H6O3.Li/c8-6-4-2-1-3-5(6)7(9)10;/h1-4,8H,(H,9,10);/q;+1/p-1
InChIKey
PSBOOKLOXQFNPZ-UHFFFAOYSA-M
Chemical Structure
2D Structure
2D structure of Lithium Salicylate
CAS: 552-38-5
CID: 23663621
Formula: C7H5LiO3
MW: 144.1
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight144.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Exact Mass144.03987245
Monoisotopic Mass144.03987245
Topological Polar Surface Area60.4 Ų
Heavy Atom Count11
Formal Charge0
Complexity138
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

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