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S100A1 Polyclonal Antibody

CAT: 0763-AN006750L-01Size: 25 µLDry Ice: NoHazardous: No
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CAT#:0763-AN006750L-01Size:25 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Small calcium binding protein that plays important roles in several biological processes such as Ca2+ homeostasis, chondrocyte biology and cardiomyocyte regulation. In response to an increase in intracellular Ca2+ levels, binds calcium which triggers conformational changes .These changes allow interactions with specific target proteins and modulate their activity.Regulates a network in cardiomyocytes controlling sarcoplasmic reticulum Ca2+ cycling and mitochondrial function through interaction with the ryanodine receptors RYR1 and RYR2, sarcoplasmic reticulum Ca2+-ATPase/ATP2A2 and mitochondrial F1-ATPase. Facilitates diastolic Ca2+ dissociation and myofilament mechanics in order to improve relaxation during diastole.
Abbreviation
S100A1
UniProt
P23297
Host
Rabbit
Reactivity
Mouse
Immunogen
Recombinant Human S100A1 protein expressed by E.coli
Target
S100A; S100A1; Bpb; NEF; Protein S100-A1; S100; S100 alpha; S100 beta; S100 calcium binding protein A1; S100 calcium binding protein B; S100 calcium-binding protein A1; S-100 protein alpha chain; S100 protein alpha polypeptide; S-100 protein subunit alpha; S100-alpha; S100B; S100beta; S100A1
Clonality
Polyclonal
Conjugation
Unconjugated
Applications
WB
Field of Research
Neuroscience; Signal Transduction; Tags & Cell Markers
Purification
Antigen Affinity Purification
Concentration
1 mg/mL
Dilution
WB 1:250-1:500
Buffer
PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol, pH7.4
Shipping Conditions
The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
11 kDa
Observed Molecular Weight
12 kDa
Isotype
IgG
Product Datasheet
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