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Grifolin

CAT: 0804-HY-N9271-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N9271-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Grifolin is an antineoplastic agent can be isolated from the mushroom Albatrellus confluens and significantly induces apoptosis[1].
CAS Number
6903-07-7
UNSPSC
12352005
Target
Apoptosis
Type
Natural Products
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/grifolin.html
Purity
97.0
Solubility
10 mM in DMSO
Smiles
OC1=CC(C)=CC(O)=C1C/C=C(C)/CC/C=C(C)/CC/C=C(C)\C
Molecular Formula
C22H32O2
Molecular Weight
328.49
References & Citations
[1]Ye M, et al. Grifolin, a potential antitumor natural product from the mushroom Albatrellus confluens, induces cell-cycle arrest in G1 phase via the ERK1/2 pathway. Cancer Lett. 2007 Dec 18;258 (2) :199-207.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Natural Products
Clinical Information
No Development Reported

Chemical Information

Grifolin

Grifolin is a sesquiterpenoid.

CAS Number6903-07-7
PubChem CID5372312
IUPAC Name5-methyl-2-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trienyl]benzene-1,3-diol
Molecular FormulaC22H32O2
Molecular Weight328.5
XLogP7.2
Topological Polar Surface Area40.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count8
Heavy Atom Count24
Formal Charge0
Complexity443
SMILES
CC1=CC(=C(C(=C1)O)C/C=C(\C)/CC/C=C(\C)/CCC=C(C)C)O
InChI
InChI=1S/C22H32O2/c1-16(2)8-6-9-17(3)10-7-11-18(4)12-13-20-21(23)14-19(5)15-22(20)24/h8,10,12,14-15,23-24H,6-7,9,11,13H2,1-5H3/b17-10+,18-12+
InChIKey
PZHNKNRPGLTZPO-VZRGJMDUSA-N
Chemical Structure
2D Structure
2D structure of Grifolin
CAS: 6903-07-7
CID: 5372312
Formula: C22H32O2
MW: 328.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight328.5
XLogP37.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count2
Rotatable Bond Count8
Exact Mass328.240230259
Monoisotopic Mass328.240230259
Topological Polar Surface Area40.5 Ų
Heavy Atom Count24
Formal Charge0
Complexity443
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count2
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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