CK1-IN-1

CK1-IN-1

• CAS Number: 1784751-20-7
• UNSPSC Description: CK1-IN-1 is a casein kinase 1 (CK1) inhibitor extracted from patent WO2015119579A1, compound 1c, has IC50s of 15 nM, 16 nM, 73 nM for CK1δ, and CK1ε, p38σ MAPK, respectively[1].
• Target Antigen: Casein Kinase
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Stem Cell/Wnt
• Applications: COVID-19-anti-virus
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/ck1-in-1.html
• Purity: 99.35
• Solubility: DMSO : 62.5 mg/mL (ultrasonic)|H2O : < 0.1 mg/mL
• Smiles: FC1=CC=C(C2=C(C3=CC=NC=C3)NC(C4=CC=C5C=CC=CC5=C4F)=N2)C=C1
• Molecular Weight: 383.39
• References & Citations: [1]Filip LACO,et al. 2,4,5-tri-substituted azole-based casein kinase 1 inhibitors as inducers for cardiomyogenesis. WO2015119579A1.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported