Products for Research Use Only

Carfilzomib

CAT: 0400-SIH-544-25MGSize: 25 mgDry Ice: NoHazardous: No
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CAT#:0400-SIH-544-25MGSize:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Carfilzomib / PR-17 is an irreversible proteasome inhibitor that targets the chymotrypsin-like beta5 subunit of 20S proteasome. It can arrest the cell cycle and trigger apoptosis in tumor cell lines.
Description
20S Proteasome inhibitor
CAS Number
868540-17-4
Product Name Alternative
(αS) -α-[[2- (4-morpholinyl) acetyl]amino]benzenebutanoyl-L-leucyl-N-[ (1S) -3-methyl-1-[[ (2R) -2-methyl-2-oxiranyl]carbonyl]butyl]-L-phenylalaninamide, PR-17, Carfilzomib, Kyprolis, Carfilzomib (PR-171), PR-171, UNII-72X6E3J5AR
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cancer | Cancer Growth Inhibitors | Proteasome Inhibitors
Purity
>98% (TLC) ; NMR (Conforms)
Weight
0.025
Format
White powder
Solubility
Soluble in DMSO (80 mg/ml), or ethanol (25 mg/ml)
Molecular Formula
C40H57N5O7
Molecular Weight
719.9
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

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