Phytosphingosine

• Background:

  Phytosphingosine is a naturally occurring component found in yeast, plants and animals. In yeast, it is involved in mediating the heat stress response. Phytosphingosine has been found to be pro-apoptotic in certain cancer cell lines. It is thought to activate the p38 MAPK pathway, followed by release of cytochrome c and activation of caspase 3, ultimately leading to programed cell death.

• Description:

  Kinase Activator

• Product Name Alternative:

  (2S,3R,4R) -Octadecane-1,2,3,4-tetraol

• UNSPSC:

  41116105

• Type:

  Activator

• Source:

  Isolated from Saccharomyces cerevisiae

• Field of Research:

  Cancer | Oxidative Stress

• Purity:

  >98% (TLC) ; NMR (Conforms)

• Weight:

  0.005

• Format:

  White powder

• Solubility:

  Soluble to 2 mg/ml in ethanol

• Molecular Formula:

  C18H39NO3

• Molecular Weight:

  317.5

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Fischer C., et al. (2013) Skin Pharmacol Physiol. 26(1): 36-44.

• CAS Number:

  554-62-1