SR 3576

• Background:

  SR 3576 is a highly potent and selective JNK3 inhibitor. SR 3576 is a pyrazolourea compound and is cell-permeable.

• Description:

  JNK3 kinase inhibitor

• Product Name Alternative:

  SR3576, 3- (5- (3-m-Tolylureido) -1H-indazol-1-yl) -N- (3,4,5-trimethoxyphenyl) benzamide, 3-[4-[[[ (3-Methylphenyl) amino]carbonyl]amino]-1H-pyrazol-1-yl]-N- (3,4,5-trimethoxyphenyl) -benzamide

• UNSPSC:

  41116105

• Type:

  Inhibitor

• Source:

  Synthetic

• Field of Research:

  Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

• Purity:

  ≥98% (HPLC)

• Weight:

  0.005

• Format:

  Off White solid

• Solubility:

  Soluble to 100 mM in DMSO

• Molecular Formula:

  C27H27N5O5

• Molecular Weight:

  501.5

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Kamenecka T., et al. (2009) J. Biol. Chem. 284(19): 12853–12861.

• CAS Number:

  1164153-22-3