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BIBW 2992

CAT: 0400-SIH-496-5MGSize: 5 mgDry Ice: NoHazardous: No
CAT#:0400-SIH-496-5MGSize:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
BIBW 2992 is a potent and irreversible ErbB inhibitor. It has also been shown to inhibit EGFR/Neu.
Description
EGFR, HER2 kinase inhibitor
CAS Number
850140-72-6
Product Name Alternative
Afatinib, N-​[4-​[ (3-​chloro-​4-​fluorophenyl) amino]-​7-​[[ (3S) -​tetrahydro-​3-​furanyl]oxy]-​6-​quinazolinyl]-​4-​ (dimethylamino) -​2-​butenamide
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors
Purity
>99%
Weight
0.005
Format
Crystalline solid
Solubility
Soluble in DMSO at 200 mg/ml; in ethanol at 25 mg/ml
Molecular Formula
C24H25ClFN5O3
Molecular Weight
485.9
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Ioannou, N., et al. (2011) Br. J. Cancer. 105(10): 1554–1562.

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