WHI P131

• Background :

  WHI P131 also known as Janex-1, is a reversible, potent, and specific inhibitor of JAK3. WHI P131 is cell permeable. It has been seen to inhibit glioblastoma cell adhesion and migration, as well as, thrombin-induced platelet aggregation.

• Description :

  JAK3 kinase inhibitor

• Product Name Alternative :

  WHI-P131, Janex 1, 4-​[ (6, ​7-​dimethoxy-​4-​quinazolinyl) amino]-​phenol

• UNSPSC :

  41116105

• Type :

  Inhibitor

• Source :

  Synthetic

• Field of Research :

  Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

• Purity :

  ≥98%

• Weight :

  0.05

• Format :

  White to off-white solid

• Solubility :

  Soluble in DMSO (~1 mg/ml), and DMF (~1 mg/ml)

• Molecular Formula :

  C16H15N3O3

• Molecular Weight :

  297.3

• Precautions :

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations :

  1. Sudbeck E.A., et al. (1999) Clin. Cancer Res: J. Am. Asso. Cancer Res. 5(6): 1569–1582.

• CAS Number :

  202475-60-3