P131

• Target :

  PROTAC Linker

• Related Pathways :

  PROTAC

• Bioactivity :

  P131 is a PROTAC molecule consisting of a cereblon ligand based on Pomalidomide and IBT6A, linked via a PEG linker. P131 effectively degrades both wild-type and C481S mutant BTK with nanomolar potency.

• Smiles :

  NC1=C2C(N(N=C2C3=CC=C(OC4=CC=CC=C4)C=C3)[C@H]5CN(C(=O)C6=CN(CCOCCOCCOCCNC7=C8C(C(=O)N(C8=O)C9C(=O)NC(=O)CC9)=CC=C7)N=N6)CCC5)=NC=N1

• Molecular Formula :

  C46H48N12O9

• Molecular Weight :

  912.948

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2360561-66-4