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P131

CAT: 0931-T206340-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T206340-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2360561-66-4
Target
PROTAC Linker
Related Pathways
PROTAC
Bioactivity
P131 is a PROTAC molecule consisting of a cereblon ligand based on Pomalidomide and IBT6A, linked via a PEG linker. P131 effectively degrades both wild-type and C481S mutant BTK with nanomolar potency.
Smiles
NC1=C2C(N(N=C2C3=CC=C(OC4=CC=CC=C4)C=C3)[C@H]5CN(C(=O)C6=CN(CCOCCOCCOCCNC7=C8C(C(=O)N(C8=O)C9C(=O)NC(=O)CC9)=CC=C7)N=N6)CCC5)=NC=N1
Molecular Formula
C46H48N12O9
Molecular Weight
912.948
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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BIPC1021-01P131
MBS3603153-01WHI-P131
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