Src I1

• Background:

  SrcI1 is a potent and competitive dual site Src kinase inhibitor. It has been shown as a potent inhibitor of the Src and Lck kinase, as well as, VEGFR2 and c-fms. SrcI1 is cell permeable and can induce apoptosis.

• Description:

  Src kinase inhibitor

• Product Name Alternative:

  6,7-Dimethoxy-N-(4-phenoxyphenyl)-4-quinazolinamine, SKI-1, Src Inhibitor-1

• CAS Number:

  179248-59-0

• UNSPSC:

  41116105

• Source:

  Synthetic

• Purity:

  ≥98% (TLC)

• Weight:

  0.005

• Format:

  Off-white solid

• Solubility:

  Soluble in DMSO (5 mg/ml)

• Molecular Formula:

  C22H19N3O3

• Molecular Weight:

  373.4

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Bain, J., et al. (2007) Biochem. J. 408(3): 297–315. 2. Leung, E. L.H., et al. (2009) Mol. Cancer. Res: MCR. 7(6): 923–932.