Dorsomorphin

• Background :

  Dorsomorphin is a potent and selective and reversible inhibitor of AMP-kinase, doing so in an ATP-competitive manner. It is also a selective inhibitor of Bone morphogenetic protein (BMP) signaling.

• Description :

  AMPK kinase inhibitor

• Product Name Alternative :

  AMPK Inhibitor, Compound C, 6-[4- (2-Piperidin-1-ylethoxy) phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine

• UNSPSC :

  41116105

• Type :

  Inhibitor

• Source :

  Synthetic

• Field of Research :

  Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

• Purity :

  ≥98% (HPLC)

• Weight :

  0.005

• Format :

  Yellow solid

• Solubility :

  Soluble in DMSO (4 mg/ml, warm)

• Molecular Formula :

  C24H25N5O

• Molecular Weight :

  399.5

• Precautions :

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations :

  1. Vucicevic L., et al. (2011) Autophagy 7(1): 40–50. 2. Yu P.B., et al. (2008). Nat. Chem. Biol. 4(1): 33–41.

• CAS Number :

  866405-64-3