Dorsomorphin

• Background:

  Dorsomorphin is a potent and selective and reversible inhibitor of AMP-kinase, doing so in an ATP-competitive manner. It is also a selective inhibitor of Bone morphogenetic protein (BMP) signaling.

• Description:

  AMPK kinase inhibitor

• Product Name Alternative:

  AMPK Inhibitor, Compound C, 6-[4- (2-Piperidin-1-ylethoxy) phenyl]-3-pyridin-4-ylpyrazolo[1,5-a]pyrimidine

• UNSPSC:

  41116105

• Type:

  Inhibitor

• Source:

  Synthetic

• Field of Research:

  Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

• Purity:

  ≥98% (HPLC)

• Weight:

  0.005

• Format:

  Yellow solid

• Solubility:

  Soluble in DMSO (4 mg/ml, warm)

• Molecular Formula:

  C24H25N5O

• Molecular Weight:

  399.5

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Vucicevic L., et al. (2011) Autophagy 7(1): 40–50. 2. Yu P.B., et al. (2008). Nat. Chem. Biol. 4(1): 33–41.

• CAS Number:

  866405-64-3