AAL-993

• Background:

  AAL-993 is a very potent inhibitor of VEGFR-1, VEGFR-2 and VEGFR-3, as well as PDGFR-β, c-Kit and CSF-1R at higher concentrations.

• Description:

  VEGFR inhibitor

• Product Name Alternative:

  2-[ (4-Pyridyl) methyl]amino-N-[3- (trifluoromethyl) phenyl]benzamide

• UNSPSC:

  41116105

• Type:

  Inhibitor

• Source:

  Synthetic

• Field of Research:

  Cell Signaling | Cancer | Apoptosis | Cardiovascular System | Cancer Growth Inhibitors | Growth Factor Receptor Inhibitors

• Purity:

  ≥98% (TLC)

• Weight:

  0.025

• Format:

  Pale yellow solid

• Solubility:

  Soluble in DMSO (>25 mg/ml) or ethanol (15 mg/ml)

• Molecular Formula:

  C20H16F3N3O

• Molecular Weight:

  371.4

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Manley P.W., et al. (2004) Biochimica Biophysica Acta. 1697(1-2): 17–27. 2. Ban H.S., Uno M., & Nakamura H. (2010) Cancer Letters. 296(1): 17–26.

• CAS Number:

  269390-77-4