Products for Research Use Only
RegisterLogin

24 (S) -Hydroxycholesterol

CAT: 0400-SIH-384-1MGSize: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0400-SIH-384-1MGSize:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Endogenous agonist for the nuclear receptor LXR. Important metabolite of cholesterol in the brain. Displays neurotoxic effects on human neuroblastoma cells. Cerebrospinal fluid concentrations of 24(S)-hydroxycholesterol are increased in patients with Alzheimer's disease and mild cognitive impairment.
Description
LXR ligand
CAS Number
474-73-7
Product Name Alternative
(3β,24S) -Cholest-5-ene-3,24-diol
UNSPSC
41116105
Type
Ligand
Source
Synthetic
Field of Research
Cell Signaling
Purity
>98%
Weight
0.001
Format
White solid
Solubility
Soluble in ethanol (10 mg/ml) or DMSO (10 mg/ml - requires warming up to ~40°C).
Molecular Formula
C27H46O2
Molecular Weight
402.7
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Chawla A., et al. (2001) Science. 294(5548): 1866-70. 2. Lütjohann D., et al. (1996) Proc. Natl. Acad. Sci. USA. 93(18): 9799-804. 3. Kölsch H., et al. (1999) Brain Res. 818(1): 171-5. 4. Schönknecht P., et al. (2002) Neurosci. Lett. 324(1): 83-5. 5. Leoni V., et al. (2006) Neurosci. Lett. 397(1-2): 83-7.

Related Products

CatalogName
SMC-447SATF4 Antibody, Clone N360A/24
SMC-447DATF4 Antibody, Clone N360A/24
SMC-447D-RPEATF4 Antibody, Clone N360A/24: RPE
SMC-447D-BIATF4 Antibody, Clone N360A/24: Biotin
SMC-447D-FITCATF4 Antibody, Clone N360A/24: FITC
SMC-447D-HRPATF4 Antibody, Clone N360A/24: HRP
SMC-447D-APCATF4 Antibody, Clone N360A/24: APC
SMC-447D-PCPATF4 Antibody, Clone N360A/24: PerCP
SMC-447D-A390ATF4 Antibody, Clone N360A/24: ATTO 390
SMC-447D-A488ATF4 Antibody, Clone N360A/24: ATTO 488

Alternative Products

CatalogName
TRC-H703710-50MG17alpha-Hydroxycholesterol
TQ0274-0127-Hydroxycholesterol
TRC-H918040-10MG24-Hydroxycholesterol
B20179267β-Hydroxycholesterol
abx283033-017a-Hydroxycholesterol
BUP06234-0125-Hydroxycholesterol
M31374-017Beta-Hydroxycholesterol
HY-124265-014β-Hydroxycholesterol
H9040-01Hydroxycholesterol, 20a-
TBW014467alpha-Hydroxycholesterol

Popular Products