Piceatannol

• Background:

  A naturally occurring resveratrol analog. Inhibits nonreceptor kinases Syk and Lyk (IC50=ca. 10M) (1). Stimulates Sirt1 (2).

• Description:

  SIRT1 activator

• Product Name Alternative:

  3,3′,4,5′-Tetrahydroxy-transstilbene; 4-[ (E) -2- (3,5-Dihydroxyphenyl) vinyl]-1,2-benzenediol

• UNSPSC:

  41116105

• Type:

  Activator

• Source:

  Synthetic

• Field of Research:

  Cell Signaling | Epigenetics and Nuclear Signaling

• Purity:

  >98% (TLC), NMR conforms

• Weight:

  0.025

• Format:

  Light Pink Solid

• Solubility:

  Soluble in 10 mg/ml DMSO or 10 mg/ml Ethanol

• Molecular Formula:

  C14H12O4

• Molecular Weight:

  244.2

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Seow C.J., et al. (2002) Eur. J. Pharmacol. 443: 189. 2. Howitz K.T., et al. (2003) Nature 425: 191.

• CAS Number:

  10083-24-6