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Garcinol

CAT: 0400-SIH-355-5MGSize: 5 mgDry Ice: NoHazardous: No
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CAT#:0400-SIH-355-5MGSize:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Potent inhibitor of histone acetyl transferases p300 (IC50=7 mM) and pCAF (IC50=5 mM) (1). Induces apoptosis in various cell lines (2). Promotes expansion of human hematopoietic stem cells(3). Cell permeable.
Description
HAT inhibitor
CAS Number
78824-30-3
Product Name Alternative
Camboginol, 3-​ (3, ​4-​dihydroxybenzoyl) -​4-​hydroxy-​8, ​8-​dimethyl-​1, ​7-​bis (3-​methyl-​2-​buten-​1-​yl) -​5-​[ (2S) -​5-​methyl-​2-​ (1-​methylethenyl) -​4-​hexen-​1-​yl]-​bicyclo[3.3.1]non-​3-​ene-​2, ​9-​dione
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cell Signaling | Epigenetics and Nuclear Signaling
Purity
>98% (TLC), NMR conforms
Weight
0.005
Format
Yellow solid
Solubility
Soluble in 25 mg/ml DMSO or 25 mg/ml Ethanol
Molecular Formula
C38H50O6
Molecular Weight
602.8
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Balasubramanyam K., et al., (2004) J. Biol. Chem. 279: 33716. 2. Parasramka M.A., et al. (2011) Nutr. Cancer. 63: 456. 3. Nishino T., et al. (2011) Nutr. PLoS One 6: e24298.

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CatalogName
HY-107569-01Garcinol

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