Garcinol

CAT: 0026-2088-5Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0026-2088-5Size:5 mg

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Description

Garcinol is a polyisoprenylated benzophenone derivative isolated from Garcinia indica. It is a potent inhibitor of histone acetyltransferases (HATs) p300 (IC50 = 7 µM) and PCAF (IC50 = 5 µM) both in vitro and in vivo. HAT activity-dependent chromatin transcription was inhibited by garcinol, but it had no effect on naked DNA transcription. Moreover, it induces apoptosis in several types of cancer cells and has anti-inflammatory actions. Garcinol promotes neurogenesis and ex vivo expansion of human hematopoietic stem cells.

Shipping Conditions

gel pack

Storage Conditions

-20°C

Shelf Life

24 months

Alternative Products

Catalog	Name
C21533-1mg	Garcinol

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