Garcinol

• Description :

  Garcinol is a polyisoprenylated benzophenone derivative isolated from Garcinia indica. It is a potent inhibitor of histone acetyltransferases (HATs) p300 (IC50 = 7 µM) and PCAF (IC50 = 5 µM) both in vitro and in vivo. HAT activity-dependent chromatin transcription was inhibited by garcinol, but it had no effect on naked DNA transcription. Moreover, it induces apoptosis in several types of cancer cells and has anti-inflammatory actions. Garcinol promotes neurogenesis and ex vivo expansion of human hematopoietic stem cells.

• Shipping Conditions :

  gel pack

• Storage Conditions :

  -20°C

• Shelf Life :

  24 months