IU1

• Background:

  Selective inhibitor of Usp14 (IC50<4 M). Enhances proteasome activity and substrate proteolysis. Cell permeable.

• Description:

  Usp-14 inhibitor

• Product Name Alternative:

  1-[1- (4-Fluoro-phenyl) -2,5-dimethyl-1H-pyrrol-3-yl]-2-pyrrolidin-1-yl-ethanone

• UNSPSC:

  41116105

• Type:

  Inhibitor

• Source:

  Synthetic

• Field of Research:

  Cancer | Apoptosis

• Purity:

  >98%

• Weight:

  0.05

• Format:

  Beige Solid

• Solubility:

  Soluble in 30 mg/ml DMSO, 15 mg/ml Ethanol

• Molecular Formula:

  C18H21FN2O

• Molecular Weight:

  300.4

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Lee B.H., et al. (2010) Nature 467: 1179. 2. Lee B.H., et al. (2010) Mol. Cell. Proteomics 10: R1100003871.

• CAS Number:

  314245-33-5