IU1

• Background :

  Selective inhibitor of Usp14 (IC50<4 M). Enhances proteasome activity and substrate proteolysis. Cell permeable.

• Description :

  Usp-14 inhibitor

• Product Name Alternative :

  1-[1- (4-Fluoro-phenyl) -2,5-dimethyl-1H-pyrrol-3-yl]-2-pyrrolidin-1-yl-ethanone

• UNSPSC :

  41116105

• Type :

  Inhibitor

• Source :

  Synthetic

• Field of Research :

  Cancer | Apoptosis

• Purity :

  >98%

• Weight :

  0.01

• Format :

  Beige Solid

• Solubility :

  Soluble in 30 mg/ml DMSO, 15 mg/ml Ethanol

• Molecular Formula :

  C18H21FN2O

• Molecular Weight :

  300.4

• Precautions :

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations :

  1. Lee B.H., et al. (2010) Nature 467: 1179. 2. Lee B.H., et al. (2010) Mol. Cell. Proteomics 10: R1100003871.

• CAS Number :

  314245-33-5