Isradipine

• Background:

  Isradipine is a calcium channel blocker of the dihydropyridine class. It is usually used in the treatment of high blood pressure because of its anti-hypertensive properties in vivo (1). Recent studies suggest a potential use for Parkinson's disease (2).

• Description:

  L-type Ca channel blocker

• Product Name Alternative:

  Isopropyl methyl 4- (2,1,3-benzoxadiazol-4-yl) -2,6-dimethyl-1,4-dihydro-3,5-pyridinedicarboxylate, PN 200-110

• UNSPSC:

  41116105

• Type:

  Inhibitor

• Source:

  Synthetic

• Field of Research:

  Neuroscience | Ion Channels | Calcium Channels | Voltage-Gated Calcium Channels

• Purity:

  >98%

• Weight:

  0.05

• Format:

  Yellow Crystalline Solid

• Solubility:

  Soluble to 50 mM in DMSO and to 20 mM in ethanol

• Molecular Formula:

  C19H21N3O5

• Molecular Weight:

  371.39

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Wada Y., Satoh K., Taira N. (1985) J Cardiovasc Pharmacol. 7(1): 190-196. 2. Chan C.S., et al. (2007) Nature. 447: 1081-1086.

• CAS Number:

  75695-93-1