Etoposide

• Background:

  Etoposide inhibits the enzyme topoisomerase II, which unwinds DNA, and be doing so causes the DNA strand to break. Cancer cells are then less likely to be able to repair this damage (1).

• Description:

  Topoisomerase II inhibitor

• Product Name Alternative:

  (5S,5aR,8aR,9R) -9- (4-Hydroxy-3,5-dimethoxyphenyl) -8-oxo-5,5a,6,8,8a,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-5-yl 4,6-O-[ (1R) -ethylidene]-β-D-glucopyranoside

• UNSPSC:

  41116105

• Type:

  Inducer

• Source:

  Synthetic

• Field of Research:

  Cancer | Apoptosis

• Purity:

  >98%

• Weight:

  0.5

• Format:

  White solid

• Solubility:

  Soluble to 100 mM in DMSO

• Molecular Formula:

  C29H32O13

• Molecular Weight:

  588.56

• Precautions:

  Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• References & Citations:

  1. Gordaliza M., et al. (2004) Toxicon. 44(4): 441-459.

• CAS Number:

  33419-42-0