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Etoposide phosphate disodium

CAT: 0931-T38607Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T38607Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
122405-33-8
Target
Topoisomerase, Others, Autophagy, Apoptosis
Related Pathways
DNA Damage/DNA Repair, Apoptosis, Autophagy, Others
Bioactivity
Etoposide phosphate disodium (BMY-40481 disodium), a phosphate ester prodrug of etoposide, is a potent chemotherapeutic agent that selectively inhibits topoisomerase II, hindering the re-ligation of DNA strands. Regarded as the active equivalent of etoposide, it effectively induces cell cycle arrest, apoptosis, and autophagy in cancer cells.
Smiles
[Na].[H][C@]12COC(=O)[C@]1([H])[C@H](c1cc(OC)c(OP(O)(O)=O)c(OC)c1)c1cc3OCOc3cc1[C@H]2O[C@@H]1O[C@]2([H])CO[C@@H](C)O[C@@]2([H])[C@H](O)[C@H]1O
Molecular Formula
C29H31Na2O16P
Molecular Weight
712.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

CatalogName
GTR19189805Etoposide phosphate disodium
HY-13630AEtoposide phosphate (disodium)
HY-13630-01Etoposide phosphate
HY-13630R-01Etoposide phosphate (Standard)
BIFK0022Etoposide 4'-Phosphate

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