RegisterLogin

Taxol

CAT: 400-SIH-239-50MGSize: 50 mgDry Ice: NoHazardous: No
50 mgSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1Product image 2
1 / 2
Background
Paclitaxel is a mitotic inhibitor that promotes and stabilizes tubulin polymerization, causing cell cycle arrest (1). Induces autocatalytic activation of caspase-10 in CCRF-HSB-2 cells, triggering apoptosis (2).
Description
Microtubule stabilizer
CAS Number
33069-62-4
Product Name Alternative
(2α,5β,7β,10β,13α) -4,10-Diacetoxy-13-{[ (2R,3S) -3- (benzoylamino) -2-hydroxy-3-phenylpropanoyl]oxy}-1,7-dihydroxy-9-oxo-5,20-epoxytax-11-en-2-yl benzoate, Paclitaxel
UNSPSC
41116105
Type
Inducer
Source
Synthetic
Field of Research
Cancer | Apoptosis
Purity
>98% (TLC) ; NMR (Conforms)
Weight
0.05
Format
White solid
Solubility
Soluble in DMSO, ethanol or acetonitrile
Molecular Formula
C47H51NO14
Molecular Weight
853.9
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Wani M., Taylor H., Wall M., Coggon P., and McPhail A. (1971) J Am Chem Soc. 93(9): 2325-2327. 2. Park S.J., et al. (2004) J Biol Chem. 279(49): 51057-51067.

Related Products

CatalogName

Alternative Products

CatalogName
1097/50Taxol
1097/10Taxol
sc-201439Taxol
abx076600-01Taxol
MC11073-01Taxol
sc-201439ETaxol
sc-201439ATaxol
sc-201439DTaxol
sc-201439BTaxol
sc-201439CTaxol

Popular Products