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6FC-GABA-Taxol

CAT: 0931-T209834-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T209834-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
3055969-34-8
Target
Others
Related Pathways
Others
Bioactivity
6FC-GABA-Taxol is a cell-permeable fluorescent probe created by linking 6FC with the anticancer drug paclitaxel (Taxol) through γ-aminobutyric acid (GABA) . It binds to microtubules in live cells, allowing imaging via confocal microscopy. Additionally, 6FC-GABA-Taxol enables the quantification of microtubule binding using flow cytometry without efflux inhibitors.
Smiles
O(C(C)=O)[C@]12[C@@]3([C@@](C)([C@@H](OC(CCCNC(=O)C4=CC=5C(OC4=O)=CC(O)=C(F)C5)=O)C[C@]1(OC2)[H])C(=O)[C@H](OC(C)=O)C=6C(C)(C)[C@](O)([C@H]3OC(=O)C7=CC=CC=C7)C[C@H](OC([C@@H]([C@@H](NC(=O)C8=CC=CC=C8)C9=CC=CC=C9)O)=O)C6C)[H]
Molecular Formula
C61H61FN2O19
Molecular Weight
1145.14
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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