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Mifepristone (RU486)

CAT: 0400-SIH-211-500MGSize: 500 mgDry Ice: NoHazardous: No
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CAT#:0400-SIH-211-500MGSize:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Mifepristone is a progesterone receptor antagonist used as an abortifacient. It is also an antiglucocorticoid and an antiandrogen. Its relative binding affinity at the progesterone receptor is twice that of progesterone, its affinity at the glucocorticoid receptor is 3x that of dexamethasone, and more than 10 times that of cortisol (1).
Description
Glucocorticoid antagonist
CAS Number
84371-65-3
Product Name Alternative
(11β,17β) -11-[4- (Dimethylamino) phenyl]-17-hydroxy-17- (1-propyn-1-yl) estra-4,9-dien-3-one, RU486, RU 38486
UNSPSC
41116105
Type
Inhibitor
Source
Synthetic
Field of Research
Cancer | Apoptosis
Purity
>98%
Weight
0.5
Format
Yellow solid
Solubility
Soluble to 100 mM in DMSO, and to 50 mM in ethanol
Molecular Formula
C29H35NO2
Molecular Weight
429.6
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Heikinheim O., Kekkonen R. and Lahteenmaki P. (2003) Contraception. 68(6): 421-426.

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