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BRCA1 Antibody

CAT: 0864-A40803-50UGSize: 50 µgDry Ice: NoHazardous: No
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CAT#:0864-A40803-50UGSize:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
9007-83-4
Gene Aliases
BRCA 1, BRCA1, BRCA1 DNA repair associated, BRCA1/BRCA2 containing complex subunit 1, BRCA1/BRCA2-containing complex, subunit 1, BRCA1_HUMAN, BRCAI, BRCC 1, BRCC1, Breast and ovarian cancer susceptibility protein 1, Breast Cancer 1, Breast Cancer 1 Early Onset, Breast cancer type 1 susceptibility protein, BROVCA1, FANCS, IRIS, PNCA4, PPP1R53, Protein phosphatase 1 regulatory subunit 53, PSCP, RING finger protein 53, RNF53
UniProt
P38398
Host
Rabbit
Antigen Species
Human
Reactivity
Human
Target Antigen
Synthesized peptide derived from Human BRCA1 around the non-phosphorylation site of S1457.
Target
BRCA1
Clonality
Polyclonal
Conjugation
Non-conjugated
Applications
WB, ELISA, WB:1:500-1:2000, ELISA:1:5000
Field of Research
Epigenetics and Nuclear Signaling
Purification Method
Antigen affinity purified
Form
Liquid
Buffer
PBS, 50% glycerol, 0.5% BSA, 0.02% sodium azide, pH 7.4.
Storage Conditions
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Fragment
IgG

UniProtKB · P38398

Breast cancer type 1 susceptibility protein

BRCA1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P38398
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
BRCA1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.3.2.27
Processing
—
Secondary accessions
E9PFZ0, O15129, Q1RMC1, Q3LRJ0, Q3LRJ6, Q6IN79, Q7KYU9
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationIsopeptide bondPhosphoproteinUbl conjugation

Molecular function

ActivatorDNA-bindingTransferase

Coding sequence diversity

Alternative initiationAlternative splicing

Biological process

Cell cycleDNA damageDNA recombinationDNA repairTranscriptionTranscription regulationUbl conjugation pathway

Cellular component

ChromosomeCytoplasmNucleus

Disease

Disease variantFanconi anemiaTumor suppressor

Ligand

Metal-bindingZinc

Domain

RepeatZinc-finger

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