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PHOP

CAT: 0804-HY-118210Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-118210Size:1 Each
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Description
PHOP is a fatty acid amide hydrolase (FAAH) inhibitor used to assess inhibitory activity in a fluorometric assay. PHOP can determine FAAH activity by measuring the amount of 4-pyridin-1-ylbutyric acid released by the enzyme in rat brain microsomes. PHOP demonstrates potential as a FAAH inhibitor and can directly measure FAAH activity by reversed-phase HPLC and fluorescence detection, providing a basis for the development of new inhibitors.
CAS Number
288862-83-9
UNSPSC
12352005
Hazard Statement
H302
Target
FAAH
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/phop.html
Smiles
O=C(CCCCCC1=CC=CC=C1)C2=NC3=C(O2)C=CC=N3
Molecular Formula
C18H18N2O2
Molecular Weight
294.35
Precautions
P264-P270-P330-P501
References & Citations
[1]High-performance liquid chromatographic assay with fluorescence detection for the evaluation of inhibitors against fatty acid amide hydrolase
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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