Recombinant Human Meteorin-like protein (METRNL)

Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Dry Ice Shipment: No

Alternative Products

Cat	Name
MBS1387703-02	Recombinant Human Meteorin-like protein
MBS1387703-03	Recombinant Human Meteorin-like protein
MBS141369-01	Recombinant Human Meteorin-Like Protein
MBS141369-04	Recombinant Human Meteorin-Like Protein
MBS141369-03	Recombinant Human Meteorin-Like Protein
MBS1387703-01	Recombinant Human Meteorin-like protein
MBS1387703-04	Recombinant Human Meteorin-like protein
MBS1387703-05	Recombinant Human Meteorin-like protein
MBS141369-02	Recombinant Human Meteorin-Like Protein
90-330	Meteorin-like Recombinant Protein

CAT:

399-CSB-EP731035HU-03

Size:

20 µg

Price:

Ask

For price, please contact [email protected].

Recombinant Human Meteorin-like protein (METRNL)

Gene Name: METRNL
UniProt: Q641Q3
Expression Region: 46-311aa
Organism: Homo sapiens
Target Sequence: QYSSDRCSWKGSGLTHEAHRKEVEQVYLRCAAGAVEWMYPTGALIVNLRPNTFSPARHLTVCIRSFTDSSGANIYLEKTGELRLLVPDGDGRPGRVQCFGLEQGGLFVEATPQQDIGRRTTGFQYELVRRHRASDLHELSAPCRPCSDTEVLLAVCTSDFAVRGSIQQVTHEPERQDSAIHLRVSRLYRQKSRVFEPVPEGDGHWQGRVRTLLECGVRPGHGDFLFTGHMHFGEARLGCAPRFKDFQRMYRDAQERGLNPCEVGTD
Tag: N-terminal 6xHis-tagged
Source: E.coli
Field of Research: Cell Biology
Assay Type: Developed Protein
Relevance: Hormone induced following exercise or cold exposure that promotes energy expenditure. Induced either in the skeletal muscle after exercise or in adipose tissue following cold exposure and is present in the circulation. Able to stimulate energy expenditure associated with the browning of the white fat depots and improves glucose tolerance. Does not promote an increase in a thermogenic gene program via direct action on adipocytes, but acts by stimulating several immune cell subtypes to enter the adipose tissue and activate their prothermogenic actions. Stimulates an eosinophil-dependent increase in IL4 expression and promotes alternative activation of adipose tissue macrophages, which are required for the increased expression of the thermogenic and anti-inflammatory gene programs in fat. Required for some cold-induced thermogenic responses, suggesting a role in metabolic adaptations to cold temperatures.
Purity: Greater than 85% as determined by SDS-PAGE.
Activity: Not Test
Length: Full Length of Mature Protein
Form: Liquid or Lyophilized powder
Buffer: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Molecular Weight: 34 kDa
References & Citations: "Meteorin-like is a hormone that regulates immune-adipose interactions to increase beige fat thermogenesis." Rao R.R., Long J.Z., White J.P., Svensson K.J., Lou J., Lokurkar I., Jedrychowski M.P., Ruas J.L., Wrann C.D., Lo J.C., Camera D.M., Lachey J., Gygi S., Seehra J., Hawley J.A., Spiegelman B.M. Cell 157:1279-1291 (2014)
Storage Conditions: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

Complementary Product Range

Our range of products, including Recombinant Human Meteorin-like protein (METRNL), falls within the same field of application and can be used across various research projects. These products are carefully selected for their high performance and reliability, supporting the diverse needs of modern laboratories. Whether for ongoing studies or future experiments, they are designed to help researchers achieve their scientific goals. Here are some related products that may be of interest for similar or future applications:

Each item in our collection, is tested for precision and quality, ensuring dependable solutions for your research. As we continue to incorporate the latest advancements, Gentaur ensures that our product range remains relevant and versatile, providing you with the tools needed for both current and future projects.

Find us on

Cat	Name
CSB-EP731035HU-03	Recombinant Human Meteorin-like protein (METRNL)
CSB-EP731035HUe0-02	Recombinant Human Meteorin-like protein (METRNL)
CSB-YP731035HU-02	Recombinant Human Meteorin-like protein (METRNL)
CSB-YP731035HU-01	Recombinant Human Meteorin-like protein (METRNL)
CSB-YP731035HU-03	Recombinant Human Meteorin-like protein (METRNL)
CSB-EP731035HUe0-03	Recombinant Human Meteorin-like protein (METRNL)
CSB-EP731035HU-02	Recombinant Human Meteorin-like protein (METRNL)
CSB-EP731035HUe0-01	Recombinant Human Meteorin-like protein (METRNL)
CSB-MP731035HU-03	Recombinant Human Meteorin-like protein (METRNL)
CSB-MP731035HU-01	Recombinant Human Meteorin-like protein (METRNL)