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Recombinant Human Meteorin (METRN)

CAT: 0399-CSB-EP892322HUa0-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0399-CSB-EP892322HUa0-01Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
C16orf23
Abbreviation
Recombinant Human METRN protein
Gene Name
METRN
UniProt
Q9UJH8
Expression Region
24-293aa
Organism
Homo sapiens (Human)
Target Sequence
GYSEERCSWRGSGLTQEPGSVGQLALACAEGAVEWLYPAGALRLTLGGPDPRARPGIACLRPVRPFAGAQVFAERAGGALELLLAEGPGPAGGRCVRWGPRERRALFLQATPHQDISRRVAAFRFELREDGRPELPPQAHGLGVDGACRPCSDAELLLAACTSDFVIHGIIHGVTHDVELQESVITVVAARVLRQTPPLFQAGRSGDQGLTSIRTPLRCGVHPGPGTFLFMGWSRFGEARLGCAPRFQEFRRAYEAARAAHLHPCEVALH
Tag
N-terminal 6xHis-tagged
Type
In Stock Protein
Source
E.coli
Field of Research
Neuroscience
Relevance
Involved in both glial cell differentiation and axonal network formation during neurogenesis. Promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. Also induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia.
Endotoxin
Not test
Purity
Greater than 85% as determined by SDS-PAGE.
Activity
Not Test
Form
Liquid or Lyophilized powder
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Function
Involved in both glial cell differentiation and axonal network formation during neurogenesis. Promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. Also induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia (By similarity) .
Molecular Weight
33.1 kDa
References & Citations
"Maternal Serum Meteorin Levels and the Risk of Preeclampsia." Garces M.F., Sanchez E., Cardona L.F., Simanca E.L., Gonzalez I., Leal L.G., Mora J.A., Bedoya A., Alzate J.P., Sanchez A.Y., Eslava-Schmalbach J.H., Franco-Vega R., Parra M.O., Ruiz-Parra A.I., Dieguez C., Nogueiras R., Caminos J.E. PLoS ONE 10:e0131013-e0131013 (2015)
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Protein Length
Full Length of Mature Protein

UniProtKB · Q9UJH8

Meteorin

METRN_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9UJH8
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
METRN
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q9UJH9
Protein keywords

Molecular function

Developmental protein

Biological process

DifferentiationNeurogenesis

PTM

Disulfide bond

Technical term

Proteomics identificationReference proteome

Cellular component

Secreted

Domain

Signal

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