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Secologanic acid

CAT: 0804-HY-N7895-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N7895-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Secologanic acid is a secoiridoid glycoside. Secologanic acid inhibits NO production, the relative expression of AKT and p-AKT. Secologanic acid shows anti-inflammatory activity[1][2].
CAS Number
60077-46-5
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Akt; NO Synthase
Type
Natural Products
Related Pathways
Immunology/Inflammation; PI3K/Akt/mTOR
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/secologanic-acid.html
Purity
98.02
Solubility
H2O : 25 mg/mL (ultrasonic)
Smiles
O=C1C2=CO[C@@H](O[C@H]3[C@@H]([C@H]([C@@H]([C@@H](CO)O3)O)O)O)[C@H](C=C)[C@]2([H])CC(O)O1
Molecular Formula
C16H22O10
Molecular Weight
374.34
Precautions
H302, H315, H319, H335
References & Citations
[1]Tamara L Meragelman, et al. Modified secoiridoid from Acicarpha tribuloides and inhibition of nitric oxide production in LPS-activated macrophages. Phytochemistry. 2006 Jul;67 (14) :1534-8.|[2]Guo X, et al. Network Pharmacology-Based Identification of Potential Targets of Lonicerae japonicae Flos Acting on Anti-Inflammatory Effects. Biomed Res Int. 2021 Sep 20;2021:5507003.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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