TRC-766

• Description :

  TRC-766 is a negative control of RTC-5 (TRC-382) . TRC-766 binds protein phosphatase 2A (PP2A) and does not activate the phosphatase[1].

• Product Name Alternative :

  DBK-766

• UNSPSC :

  12352005

• Target :

  Phosphatase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Others

• Assay Protocol :

  https://www.medchemexpress.com/trc-766.html

• Purity :

  98.07

• Solubility :

  DMSO : 150 mg/mL (ultrasonic)

• Smiles :

  O=S(C1=CC=C(OC(F)(F)F)C=C1)(N(CCCN2C3=CC(Cl)=CC=C3CCC4=CC=CC=C42)C)=O

• Molecular Formula :

  C25H24ClF3N2O3S

• Molecular Weight :

  524.98

• References & Citations :

  [1]Kimberly McClinch, et al. Small-Molecule Activators of Protein Phosphatase 2A for the Treatment of Castration-Resistant Prostate Cancer. Cancer Res. 2018 Apr 15;78 (8) :2065-2080.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1810734-44-1]