BGC-20-1531 (free base)

BGC-20-1531 (free base)

• CAS Number: 736183-35-0
• UNSPSC Description: BGC-20-1531 (PGN 1531) free base is a potent and selective prostanoid EP4 receptor antagonist, with a pKB of 7.6. BGC-20-1531 free base has the potential for the research of migraine headache[1].
• Target Antigen: Prostaglandin Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/bgc-20-1531-free-base.html
• Purity: 98.05
• Solubility: DMSO : 250 mg/mL (ultrasonic)
• Smiles: O=C(C1=CC(COC2=CC=C(C3=NC=C(OC)C=C3)C=C2)=C(C)O1)NS(=O)(C4=CC=CC=C4C)=O
• Molecular Weight: 492.54
• References & Citations: [1]Maubach KA, et al. BGC20-1531, a novel, potent and selective prostanoid EP receptor antagonist: a putative new treatment for migraine headache. Br J Pharmacol. 2009;156(2):316-327.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: Phase 2