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(5R) -5-Hydroxytriptolide

CAT: 0804-HY-107101-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-107101-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(5R) -5-Hydroxytriptolide is an extracted compound from Tripterygium, and shows lower cell cytotoxicity and higher immunosuppressive activity. (5R) -5-Hydroxytriptolide can be used for study of rheumatoid arthritis[1].
CAS Number
583028-68-6
Product Name Alternative
PG 701; LLDT-8; 5α-Hydroxytriptolide
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/5r-5-hydroxytriptolide.html
Purity
99.67
Smiles
CC([C@@]12[C@H]([C@H]3[C@]4([C@@]5(C)CCC6=C(COC6=O)[C@]5(O)C[C@H]7[C@@]4(O7)[C@@H]2O)O3)O1)C
Molecular Formula
C20H24O7
Molecular Weight
376.40
References & Citations
[1]Guo S, et al. (5R) -5-Hydroxytriptolide (LLDT-8) induces substantial epigenetic mediated immune response network changes in fibroblast-like synoviocytes from rheumatoid arthritis patients. Sci Rep. 2019;9 (1) :11155. Published 2019 Aug 1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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