(5R) -5-Hydroxytriptolide

• Description :

  (5R) -5-Hydroxytriptolide is an extracted compound from Tripterygium, and shows lower cell cytotoxicity and higher immunosuppressive activity. (5R) -5-Hydroxytriptolide can be used for study of rheumatoid arthritis[1].

• Product Name Alternative :

  PG 701; LLDT-8; 5α-Hydroxytriptolide

• UNSPSC :

  12352005

• Target :

  Others

• Type :

  Reference compound

• Related Pathways :

  Others

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/5r-5-hydroxytriptolide.html

• Purity :

  99.67

• Smiles :

  CC([C@@]12[C@H]([C@H]3[C@]4([C@@]5(C)CCC6=C(COC6=O)[C@]5(O)C[C@H]7[C@@]4(O7)[C@@H]2O)O3)O1)C

• Molecular Formula :

  C20H24O7

• Molecular Weight :

  376.40

• References & Citations :

  [1]Guo S, et al. (5R) -5-Hydroxytriptolide (LLDT-8) induces substantial epigenetic mediated immune response network changes in fibroblast-like synoviocytes from rheumatoid arthritis patients. Sci Rep. 2019;9 (1) :11155. Published 2019 Aug 1.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [583028-68-6]