Dimethylformamide-(S,R,S)-AHPC-CO-cyclohexane-pyrimidine-diazabicyclo

CAT:

804-HY-159594

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UNSPSC Description: Dimethylformamide-(S,R,S)-AHPC-CO-cyclohexane-pyrimidine-diazabicyclo is an E3 Ligase Ligand-Linker Conjugate. Dimethylformamide-(S,R,S)-AHPC-CO-cyclohexane-pyrimidine-diazabicyclo can be used to synthesize PROTAC SMARCA2/4-degrader-2 (HY-159453)[1].
Target Antigen: E3 Ligase Ligand-Linker Conjugates
Type: Reference compound
Related Pathways: PROTAC
Applications: Cancer-programmed cell death
Field of Research: cancer
Assay Protocol: https://www.medchemexpress.com/dimethylformamide-s-r-s-ahpc-co-cyclohexane-pyrimidine-diazabicyclo.html
Smiles: O=C(N1[C@@H](C[C@H](C1)O)C(NCC2=C(C=C(C3=C(N=CS3)C)C=C2)C(N(C)C)=O)=O)[C@H](C(C)(C)C)NC([C@H](CC4)CC[C@@H]4C5=CN=C(N=C5)N6C7CNCC6CC7)=O
Molecular Weight: 800.02
References & Citations: [1]Preparation of heterocyclic compounds as SMARCA degraders and uses thereof. USA, US20230072658A1 2020-12-17
Shipping Conditions: Room temperature
Clinical Information: No Development Reported

Cat	Name
HY-159594	Dimethylformamide-(S,R,S)-AHPC-CO-cyclohexane-pyrimidine-diazabicyclo
HY-159558	(S,R,S)-AHPC-CO-cyclohexane-C-Ph-pyrimidine-diazabicyclo
HY-159593	Ac-NH-(S,R,S)-AHPC-CO-cyclohexane-pyrimidine-diazabicyclo
HY-163933	(S,R,S)-AHPC-CO-C-cyclohexane
HY-163930	(S,R,S)-AHPC-CO-cyclohexane-C2
HY-159556	Dimethylformamide-(S,R,S)-AHPC
HY-163937	(S,R,S)-AHPC-O-CF3 -CO-cyclohexane
HY-168250	trans-(S,R,S)-AHPC-Me-Amide-cyclohexane-pyrimidine-Cl
HY-160555	(S,R,S)-AHPC-CO-C9-NH2
HY-159550	(S,R,S)-AHPC-CO-cyclohexene-Bpin