Ac-NH-(S,R,S)-AHPC-CO-cyclohexane-pyrimidine-diazabicyclo

• UNSPSC Description:

  Ac-NH-(S,R,S)-AHPC-CO-cyclohexane-pyrimidine-diazabicyclo is an E3 Ligase Ligand-Linker Conjugate. Ac-NH-(S,R,S)-AHPC-CO-cyclohexane-pyrimidine-diazabicyclo can be used to synthesize PROTAC SMARCA2/4-degrader-1 (HY-159452)[1].

• Target Antigen:

  E3 Ligase Ligand-Linker Conjugates

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  cancer

• Assay Protocol:

  https://www.medchemexpress.com/ac-nh-s-r-s-ahpc-co-cyclohexane-pyrimidine-diazabicyclo.html

• Smiles:

  O=C(N1[C@@H](C[C@H](C1)O)C(NCC2=C(C=C(C3=C(N=CS3)C)C=C2)NC(C)=O)=O)[C@H](C(C)(C)C)NC([C@H](CC4)CC[C@@H]4C5=CN=C(N=C5)N6C7CNCC6CC7)=O

• Molecular Weight:

  786.00

• References & Citations:

  [1]Preparation of heterocyclic compounds as SMARCA degraders and uses thereof. USA, US20230072658A1 2020-12-17

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported