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Cav3.3 rabbit pAb

CAT: 0855-ES20794-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES20794-01Size:50 µL
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Background
Calcium voltage-gated channel subunit alpha1 I (CACNA1I) Homo sapiens This gene encodes the pore-forming alpha subunit of a voltage gated calcium channel. The encoded protein is a member of a subfamily of calcium channels referred to as is a low voltage-activated, T-type, calcium channel. The channel encoded by this protein is characterized by a slower activation and inactivation compared to other T-type calcium channels. This protein may be involved in calcium signaling in neurons. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]
Description
Calcium voltage-gated channel subunit alpha1 I (CACNA1I) Homo sapiens This gene encodes the pore-forming alpha subunit of a voltage gated calcium channel. The encoded protein is a member of a subfamily of calcium channels referred to as is a low voltage-activated, T-type, calcium channel. The channel encoded by this protein is characterized by a slower activation and inactivation compared to other T-type calcium channels. This protein may be involved in calcium signaling in neurons. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011],
UniProt
Q9P0X4
Swiss Prot
Q9P0X4
Reactivity
Human; Rat; Mouse
Immunogen
Synthetic Peptide of Cav3.3 AA range: 210-290
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF
Concentration
1 mg/ml
Dilution
IHC 1:100-200
Molecular Weight
240kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
240kD
Fragment
IgG
Subcellular Location
Membrane; Multi-pass membrane protein.
Other Product Names
Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage-gated calcium channel subunit alpha Cav3.3; Ca (v) 3.3)
Gene ID (Human)
8911

UniProtKB · Q9P0X4

Voltage-dependent T-type calcium channel subunit alpha-1I

CAC1I_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9P0X4
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CACNA1I
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B0QY12, B0QY13, B0QY14, O95504, Q5JZ88, Q7Z6S9, Q8NFX6, Q9NZC8, Q9UH15, Q9UH30, Q9ULU9, Q9UNE6
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Ligand

Calcium

Molecular function

Calcium channelIon channelVoltage-gated channel

Biological process

Calcium transportIon transportTransport

Disease

Disease variantIntellectual disability

PTM

GlycoproteinPhosphoprotein

Cellular component

Membrane

Domain

RepeatTransmembraneTransmembrane helix

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