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Boc-C14-COOH

CAT: 0804-HY-W034599-01Size: 5 gDry Ice: NoHazardous: No
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CAT#:0804-HY-W034599-01Size:5 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Boc-C14-COOH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Boc-C14-COOH is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
CAS Number
843666-27-3
UNSPSC
12352203
Hazard Statement
H302, H312, H332
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/boc-c14-cooh.html
Purity
98.0
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C(O)CCCCCCCCCCCCCCC(OC(C)(C)C)=O
Molecular Formula
C20H38O4
Molecular Weight
342.51
Precautions
H302, H312, H332
References & Citations
[1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16 (5) :315-337.|[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27 (8) :998-985.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Non-cleavable Linker

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