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S-WJM992

CAT: 0804-HY-159603Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-159603Size:1 Each
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Description
S-WJM992 (compound 10ahb) is an antiparasitic agent that inhibits ATPase activity under high [Na+] conditions. S-WJM992 also has significant inhibitory effects on parasites that have developed PfATP4 inhibitor-resistance. S-WJM992 is a potential transmission blocker that effectively inhibits gamete development and prevents parasite transmission to mosquitoes via blood feeding[1].
UNSPSC
12352005
Target
Na+/K+ ATPase; Parasite
Type
Reference compound
Related Pathways
Anti-infection; Membrane Transporter/Ion Channel
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/s-wjm992.html
Smiles
O=C([C@](N1C)(CCC2=O)N2C3=C(C(F)=CC(C4=CN(C)N=C4)=C3)C1=O)NC5=CC(Cl)=CN=C5
Molecular Formula
C22H18ClFN6O3
Molecular Weight
468.87
References & Citations
[1]Property and Activity Refinement of Dihydroquinazolinone-3-carboxamides as Orally Efficacious Antimalarials that Target PfATP4
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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