3-Methylxanthine-13C4,15N3

3-Methylxanthine-13C4,15N3

• CAS Number: 1173018-93-3
• UNSPSC Description: 3-Methylxanthine-13C4,15N3 is the 13C-labeled and 15N-labeled 3-Methylxanthine. 3-Methylxanthine, a xanthine derivative, is a cyclic guanosine monophosphate (GMP) inhibitor, with an IC50 of 920 μM on guinea-pig isolated trachealis muscle.
• Target Antigen: Endogenous Metabolite
• Type: Isotope-Labeled Compounds
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/3-methylxanthine-13c4-15n3.html
• Solubility: 10 mM in DMSO
• Smiles: O=[13C]1[13C]2=[13C]([15N]=CN2C)[15NH][13C]([15NH]1)=O
• Molecular Weight: 173.09
• References & Citations: [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Tanaka H, et al. Inhibition of cyclic GMP phosphodiesterase by xanthine derivatives relaxes guinea-pig trachealis smooth muscle. Clin Exp Pharmacol Physiol. 1991 Mar;18(3):163-8.|[3]Yamamoto K, et al. Neurotoxic convulsions induced by theophylline and its metabolites in mice. Biol Pharm Bull. 1996 Jun;19(6):869-72.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported