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Bupropion morpholinol-d6

CAT: 0804-HY-12766S-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-12766S-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bupropion morpholinol-d6 is the deuterated form of Bupropion morpholinol. Bupropion morpholinol is a major metabolite of Bupropion. Bupropion morpholinol inhibits Dopamine, Norepinephrine transporters and the α4β2 nicotinic receptor in vitro. Bupropion morpholinol contributes to antidepressant and smoking cessation activities[1].
CAS Number
1216893-18-3
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Dopamine Transporter; Isotope-Labeled Compounds; nAChR
Type
Isotope-Labeled Compounds
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Purity
99.28
Solubility
10 mM in DMSO
Smiles
OC1(C2=CC=CC(Cl)=C2)C(C)NC(C([2H])([2H])[2H])(C([2H])([2H])[2H])CO1
Molecular Formula
C13H12D6ClNO2
Molecular Weight
261.78
Precautions
H302, H315, H319, H335
References & Citations
[1]Zhu A Z X, et al. CYP2B6 and bupropion's smoking‐cessation pharmacology: the role of hydroxybupropion[J]. Clinical Pharmacology & Therapeutics, 2012, 92 (6) : 771-777.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported