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Cefoxitin (sodium)

CAT: 0804-HY-B1117-01Size: 250 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1117-01Size:250 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cefoxitin sodium (MK-306) is a cephalosporin-class antibiotic. Cefoxitin sodium is highly stable against β-Lactamase. Cefoxitin sodium has a broad spectrum of antibacterial activity, including Gram-negative and Gram-positive bacteria[1][2][3].
CAS Number
33564-30-6
Product Name Alternative
MK-306
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Antibiotic; Bacterial; Beta-lactamase
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Cefoxitin-sodium.html
Concentration
10mM
Purity
99.69
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C(N12)=C(COC(N)=O)CS[C@]2([H])[C@@](NC(CC3=CC=CS3)=O)(OC)C1=O)O[Na]
Molecular Formula
C16H16N3NaO7S2
Molecular Weight
449.43
Precautions
H302, H315, H319, H335
References & Citations
[1]Cavalli Z, et al. Prolonged Cefoxitin Infusion Using Mobile Elastomeric Infusors In Outpatients With Bone And Joint Infection. J Bone Jt Infect. 2018 Sep 7;3 (4) :182-186.|[2]R N Brogden, et al. Cefoxitin: a review of its antibacterial activity, pharmacological properties and therapeutic use. Drugs. 1979 Jan;17 (1) :1-37.|[3]Venkata Raveendra Pothineni, et al. In vitro and in vivo evaluation of cephalosporins for the treatment of Lyme disease. Drug Des Devel Ther. 2018; 12: 2915–2921.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Citation 01
J Antimicrob Chemother. 2020 Jul 1;75 (7) :1850-1858.|Antimicrob Agents Chemother. 2025 May 23:e0024925.|bioRxiv. 2025 Jun 19.|Diagn Microbiol Infect Dis. 2025 Nov 4;114 (2) :117181.|Infect Drug Resist. 2025 Oct 4:18:5239-5247.|J Antimicrob Chemother. 2025 Nov 5:dkaf408.|J Clin Microbiol. 2025 Aug 20:e0084125.|Microbiol Spectr. 2025 May 19:e0307424.|Nat Commun. 2022 Mar 2;13 (1) :1116.|Nat Commun. 2023 Mar 22;14 (1) :1594.|Nat Microbiol. 2023 Mar;8 (3) :410-423.

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